Perilla Seed Extract

Anti-allergy*

The patients with allergies are increasing every year, and the diet is said to be one of the most important factors of this disease. Daily intake of Ω-6 fatty acids, commonly found in fish or plant oil such as safflower, are accumulated as arachidonic acid which is converted to allergic mediators.*

PERILLA SEED EXTRACT inhibits the production of allergic mediators, leukotrienes (LTs). The mediators are metabolites of arachidonic acid through 5-lipoxygenase (5-LO) pathway. PERILLA SEED EXTRACT selectively inhibits 5-LO activity (in vitro).*

PERILLA SEED EXTRACT also inhibits type IV allergy as well as TPA-induced inflammation (in vivo). Moreover, the serum IgE levels were suppressed by administration of PERILLA SEED EXTRACT, and allergic rhinitis, hay fever and urticaria were significantly improved on human.*

The functional compounds of PERILLA SEED EXTRACT are flavonoid aglycons, such as luteolin, apigenin, chrysoeriol, and rosemarinic acid. Though flavonoids are normally existing as glycosides in the plant, perilla seeds contain aglycons. It is known that antioxidative activity and lipoxygenase inhibitory activity of flavonoid aglycons are stronger than that of corresponding glycosides.*

After 2 weeks taking  Perilla Seed Extract users shown significant improvement related to sneezing, stuffy nose, itchy eyes and skin.*